Hypoglycemic agents
Jiangtangling, glibenclamide and chloride sulfonyl urea such as aspirin and C, can cause low blood coma. The reason is hypoglycemic effect of aspirin itself, and aspirin can relieve hypoglycemic drug metabolism and excretion, to enhance the hypoglycemic effect.
Anti-cancer drug methotrexate in combination with aspirin, can increase plasma concentration of methotrexate, enhancing toxicity.
Hypnotic phenobarbital (luminal) and brain-chip and other liver cells may promote the increased drug activity and speed up the metabolism of aspirin to reduce the effect.
Lipid-lowering drugs cholestyramine and aspirin and use, will form a complex, prevented the absorption.
Diuretic furosemide and aspirin drug accumulation in vivo will, increase toxicity; acetazolamide and aspirin, which can increase blood concentration of the former, causing toxicity.
New anticoagulant drugs anticoagulant, warfarin, coumarin plus aspirin for two-, enhanced inhibition of platelet function, increased risk of bleeding.
Anti-tuberculosis drugs on amino acid metabolism of sodium will be the interference of aspirin, it will affect the treatment effect, and also increase toxicity.
Anti-inflammatory analgesic
Anti-inflammatory pain, inflammatory pain, and aspirin at the same time static applications, not only can not enhance efficacy, but may cause stomach bleeding; ibuprofen and aspirin may also cause gastrointestinal bleeding.
Anti-gout drugs probenecid, Phenylbutazone and tribenuron oxazolone treatment effect could be antagonized aspirin, leading to gout attacks.
Vitamin
Aspirin can reduce the absorption of vitamin C in the intestines and can promote its excretion, resulting in decreased efficacy; vitamin B1 can promote the decomposition of aspirin, increase the stimulation of the gastric mucosa, it should not be shared.
Hormone prednisone, to plug dense pine, prednisolone caused stomach, duodenum or esophagus and colon ulcer, aspirin can exacerbate such adverse reactions.